Germany and the Cyclodextrin Science and Technology.
Abstract. The main objective of this study was to investigate different manufacturing processes claimed to promote inclusion complexation between different drugs and cyclodextrins.
Host-guest chemistry: physicochemical aspects of cyclodextrin-drug and lithium-crown ether interactions. Thesis:308555 (Thesis:308555) Find all citations by this author (default).
Biopharmaceutical production through transient gene expression (TGE) is used within industry for the rapid supply of product for early stage testing. A key requirement of the process is the large scale transfection of mammalian cells, for which the cationic polymer, polyethylenimine (PEI), is widely used. In this thesis, the mechanism of PEI mediated transfection of CHO-S cells is explored at.
New templates based on the structures of cyclodextrin and ferrocene have been developed for porphyrin nanoring syntheses. Flexibility can be taken into account of the molecular template design. The flexibility of butadiyne bonds allow the formation of a 5-porphyrin nanoring, which is the smallest fully-conjugated porphyrin nanoring to date.
The benzylidene-, isopropylidene- glucopyranosides and the silylated cyclodextrin mentioned above underwent allylation with allyl bromide, to give 2,3-di-O-allyl-glucopyranosides and heptakis(2,3-di-0-allyl)-p-CD respectively. Ring closing metathesis (RCM) with Grubb's 2nd generation catalyst of the allylated cyclodextrin yielded a complex mixture, but the allylated glucopyranosides yielded.
The present dissertation entitled, “Design of Luminescent Magnetic Nanostructures for Sensor, Drug delivery and Bioimaging Applications” is an embodiment of the investigations intended at developing simple inexpensive synthetic methods for producing luminescent carbon quantum dot and multifunctional magnetic luminescent nanostructures applicable for sensor and biomedical application.
Abstract. The first aim of the study was to introduce a practical approach to the recovery of CYCLODEXTRIN GLYCOSYLTRANSFERASE (CGTase) from Bacillus cereus using polyethylene gly.